Numb is an intracellular protein with multiple functions.The two prevalent isoforms, Numb p66 and Numb p72, are regulators of differentiation and proliferation in neuronal development.Additionally, Numb functions as cell fate determinant of stem cells and cancer stem cells and its abnormal expression has been described in several types of cancer.In
There is a growing evidence that social determinants of health influence the health outcomes.These non-medical factors, i.e., social determinants of health / mental health, are defined as the conditions in which people are born, grow, live, work and age, including the factors shaping these conditions.They either have direct effects on health and il
OBJECTIVE The objective of this study was to determine the frequency of dural tear in patients with depressed skull fractures.MATERIAL and Method This cross-sectional study was conducted in department of Neurosurgery Pakistan institute of Medical Sciences Islamabad from January 2010 to December 2011.All patients of either gender with depressed skul
The evolution of advancing Coffee computing technology has encouraged the use of finite element analysis to require constitutive models, mostly adopted extensive experimental datasets.Nevertheless, fewer material properties are required within the bilinear traction-separation relationship incorporated with the XFEM technique and require fewer compu
BACKGROUND: Diabetes Mellitus (DM) is a common metabolic disease worldwide.Electrolyte played significant roles in the normal functioning of the body, and deregulation is indicative of different types of disease and electrolyte disturbances are often reported in type 2 DM (T2DM).AIM: The aim of the study was to estimate the levels of